Abstract
Platelet-rich fibrin (PRF) as a biological scaffold is attracting clinicians’ attention, mainly because it promotes bone and soft tissue healing. As autologous material, PRF has many advantages over other platelet concentrates, such as Platelet-rich plasma (PRP) and Plasma rich in growth factors (PRGF). Among many benefits, simple preparation (centrifugation protocol) stands out because no additional anticoagulant is added to the tubes. This chapter aims to clarify the PRF membranes and sticky bone preparation together with other platelet concentrates. A few clinical cases will show how sticky bone is together with PRF membranes applicative in different oral surgery indications. Clinical and radiological check-ups demonstrated excellent therapeutic outcomes. Sticky bone and PRF membranes have regenerative potential and are advised to use in many oral surgery procedures.
Reference47 articles.
1. Costello BJ, Shah G, Kumta P, Sfeir CS. Regenerative medicine for craniomaxillofacial surgery. Oral and Maxillofacial Surgery Clinics of North America. 2010;22:33-42. DOI: 10.1016/j.coms.2009.10.009
2. Miron RJ, Zucchelli G, Pikos MA, Salama M, Lee S, Guillemette V, et al. Use of platelet-rich fibrin in regenerative dentistry: A systematic review. Clinical Oral Investigations. 2017;21:1913-1927. DOI: 10.1007/s00784-017-2133-z
3. Dean L. Blood and the cells it contains. National Center for Biotechnology Information (NCBI). National Library of Medicine. Bethesda, USA: National Institutes of Health; 2005
4. Holinstat M. Normal platelet function. Cancer Metastasis Reviews. 2017;36:195-198. DOI: 10.1007/s10555-017-9677-x
5. Blair P, Flaumenhaft R. Platelet α-granules: Basic biology and clinical correlates. Blood Reviews. 2009;23:177-189. DOI: 10.1016/j.blre.2009.04.001