Abstract
Linked color imaging (LCI), distinct from the traditional red emphasis in endoscopic imaging, utilizes narrow-band light and red signal processing to enhance contrast in mucosal color. Redness and erosion triggered by inflammation are recognized as typical signs of Helicobacter pylori (HP) infection. Notably, these visual cues are readily identifiable through the LCI mode. Leveraging the LCI observation mode significantly improves the accuracy of diagnosing gastritis associated with HP, providing accurate diagnostic performance and precise localization. LCI demonstrates superior diagnostic accuracy in detecting HP infections, including their precise localization, when compared to traditional white light endoscopy. It also holds promise for enhancing the precision of sampling for HP cultures and determining antibiotic susceptibility. Integrating LCI with the Kyoto Classification of Gastritis may enhance the endoscopic diagnosis and confirmation of HP infection eradication, subsequently augmenting the capacity of gastrointestinal endoscopists and general practitioners to identify HP infections through endoscopic imagery.