Review of an Unusual Case of Chronic Relapsing (×6) Zoster Sine Herpete: Immediate Response to High-dose Oral Acyclovir Therapy: Efficacy of the Expedited Classic Therapeutic Trial in an Era of Digital Medicine-Reference-Cited by-同舟云学术

Review of an Unusual Case of Chronic Relapsing (×6) Zoster Sine Herpete: Immediate Response to High-dose Oral Acyclovir Therapy: Efficacy of the Expedited Classic Therapeutic Trial in an Era of Digital Medicine

Published:2023-03-10 Issue: Volume:Volume 2 Page:1-18
ISSN:2754-6306
Container-title:Digital Medicine and Healthcare Technology
language:
Short-container-title:DMHT

Author:

Tisman Glenn¹

Affiliation:

1. Independent Medical Oncologist, Hypoluxo, Florida, USA

Abstract

A 79-year-old retired physician with type II diabetes mellitus and hypercholesterolemia presented to his physician complaining of recurrent severe unilateral T10 thoracic pain. This report demonstrates the effect of early high-dose oral acyclovir therapy as a diagnostic, therapeutic challenge to assist in the early diagnosis of zoster sine herpete, herpes zoster infection without dermatomal skin rash (ZSH), a clinically covert form of the more recognized herpes zoster infection with both dermatomal pain and skin rash (HZ).

Publisher

IntechOpen

Reference63 articles.

1. Breivik H, Borchgrevink PC, Allen SM, Rosseland LA, Romundstad L, Breivik Hals EK, Assessment of pain. Br J Anaesth [Internet]. 2008 Jul [cited 2021 Mar 31];101(1):17–24. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0007091217342630.

2. Hope-Simpson RE. The nature of herpes zoster: a long-term study and a new hypothesis. Proc R Soc Med [Internet]. 1965 Jan [cited 2021 Mar 9];58(1):9–20. Available from: http://journals.sagepub.com/doi/10.1177/003591576505800106.

3. Depledge DP, Sadaoka T, Ouwendijk WJD. Molecular aspects of varicella-zoster virus latency. Viruses. 2018 Jun;10(7):349.

4. Depledge DP, Ouwendijk WJD, Sadaoka T, Braspenning SE, Mori Y, Cohrs RJ, A spliced latency-associated VZV transcript maps antisense to the viral transactivator gene 61. Nat Commun [Internet]. 2018 Dec [cited 2021 Apr 14];9(1):1167. Available from: http://www.nature.com/articles/s41467-018-03569-2.

5. Depledge DP, Ouwendijk WJD, Sadaoka T, Braspenning SE, Mori Y, Cohrs RJ, A unique spliced varicella-zoster virus latency transcript represses expression of the viral transactivator gene 61. Microbiology [Internet]. 2017 Aug [cited 2021 Apr 14]. Available from: http://biorxiv.org/lookup/doi/10.1101/174797.