Long-Term Development and Health of Children Conceived by Assisted Reproductive Technologies

Author:

Belyaeva Irina А.1ORCID,Namazova-Baranova Leyla S.2ORCID,Baranov Alexander A.3ORCID,Efendieva Kamilla Y.2ORCID,Karkashadze George A.3ORCID,Dedyukina Elena S.4,Serebryakova Elena N.5ORCID,Konstantinidi Tatiana A.3,Molodchenkov Alexey I.6ORCID,Gogberashvili Tinatin Yu.3

Affiliation:

1. Research Institute of Pediatrics and Children’s Health in Clinical Research Centre № 2 of “Russian Research Center of Surgery named after academician B.V. Petrovsky”; Pirogov Russian National Research Medical University; Morozov Children’s City Hospital

2. Research Institute of Pediatrics and Children’s Health in Clinical Research Centre № 2 of “Russian Research Center of Surgery named after academician B.V. Petrovsky”; Pirogov Russian National Research Medical University

3. Research Institute of Pediatrics and Children’s Health in Clinical Research Centre № 2 of “Russian Research Center of Surgery named after academician B.V. Petrovsky”

4. Tyumen State Medical University

5. Federal State Budgetary Educational Institution of Higher Education "South-Ural State Medical University" of the Ministry of Healthcare of the Russian Federation

6. SIA «Technologies for systems analysis»; Peoples’ Friendship University of Russia

Abstract

The demographic situation in Russia requires escalation of measures to combat infertility including assisted reproductive technologies (ART). The analysis of correlations between ART and features of health and long-term development of “children from the tube” is presented. There is a high risk of dysontogeny after in vitro fertilization/intracytoplasmic sperm injection due to epigenetic disorders such as DNA methylation disorders. Living conditions, parenting, education, and health care are crucial for the healthy development of all children including those conceived by ART. The correlations between long-term cognitive development of “children from the tube” and the aspects of parenting in families are presented.

Publisher

Paediatrician Publishers LLC

Subject

Pediatrics, Perinatology and Child Health

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1. Scientific Research in the Field of Children’s Health and Development;Annals of the Russian academy of medical sciences;2024-01-22

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