New Possibilities of Preventive Immunization for Rotavirus Infection in Russian Federation. Overview of the Innovative Rotavirus Vaccine Profile

Author:

Namazova-Baranova Leyla S.1ORCID,Fedoseenko Marina V.1ORCID,Kalyuzhnaia Tatiana A.1ORCID,Shakhtakhtinskaya Firuza Ch.1ORCID,Tolstova Svetlana V.2,Selvyan Arevaluis M.2

Affiliation:

1. Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University

2. Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery

Abstract

This article is devoted to the issue of rotavirus infection in pediatric population and demonstrates worldwide prevalence of rotavirus among the causes of viral gastroenteritis and its persistent leadership among the causes of fatal diarrhea in children of the first 5 years of life. Specific prevention of rotavirus infection has been actively carried out around the world since 2005. Nowadays, we have adequate experience in the use of various rotavirus vaccines bolstered by their implementation in immunisation schedules for infants. The authors provide data on the efficacy and safety of rotavirus vaccines licensed and used in Russian Federation, involving the results of studies on safety, immunological and clinical efficacy of one of the pentavalent rotavirus vaccines.

Publisher

Paediatrician Publishers LLC

Subject

Pulmonary and Respiratory Medicine,Pediatrics, Perinatology and Child Health

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