Efficacy and Safety of Peptide Vaccine in Prevention of SARS-CoV-2 Infection: Prospective Study among Healthcare Professionals

Author:

Namazova-Baranova Leyla S.1ORCID,Fedoseenko Marina V.2ORCID,Shakhtakhtinskaya Firuza Ch.2ORCID,Kaliuzhnaia Tatiana A.2ORCID,Soloshenko Margarita A.3ORCID,Tolstova Svetlana V.3ORCID,Selvyan Arevaluis M.3ORCID,Privalova Tatiana E.2,Timoshkova Snezhana D.4ORCID,Melnikova Albina A.5ORCID,Gorelov Aleksandr V.6ORCID,Ploskireva Antonina A.6ORCID,Mustafina Ilina Z.5ORCID,Melekhina Elena V.6ORCID,Usenko Denis V.6ORCID,Ponezheva Zhanna B.6ORCID,Omarova Khadizhat G.6ORCID

Affiliation:

1. Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”; Pirogov Russian National Research Medical University; Belgorod National Research University

2. Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”; Pirogov Russian National Research Medical University

3. Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”

4. Pirogov Russian National Research Medical University

5. Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing

6. Central Research Institute of Epidemiology of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing

Abstract

The pandemic caused by the new coronavirus infection remains the topical health issue and constitutes serious threat to the entire world. Nowadays, active immunization against new type of coronavirus infection continues in Russian Federation and in all other countries. Vaccination is the crucial component in comprehensive program for COVID-19 prevention and control. Mass immunization of population can prevent both admissions and hospitalization in conditions of high incidence of COVID-19 and thereby reduce the burden on the health system. Despite the remaining complications in combating the SARS-CoV-2 pandemic, preventive vaccination is by far the most effective method for protection against this infection Clinical studies on the efficacy of various preventive vaccinations in different regions of the world are extremely relevant especially under conditions of the emergency use authorization for vaccines against new coronavirus infection, the changing epidemiological situation, and the wide variability of different types of vaccines. All countries will need continuously updated data on vaccine efficacy to address new challenges such as weakening post-vaccine protection, new SARS-CoV-2 strains, and need for other preventive measures to mitigate the pandemic.

Publisher

Paediatrician Publishers LLC

Subject

Pediatrics, Perinatology and Child Health

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