Author:
Bhattacharya Gautam,K Dhar Tarun,Kathleen Bhattacharya F,A I Siddiqui Kazi
Abstract
Phaseolinone was mutagenic to excision-repair-deficient strains of Escherichia coli WP2 and also to Salmonella typhimurium TA100. The repair test was indicative of covalent binding of the toxin to DNA. The side-chain epoxide and the hydroxy groups of the molecule were found to be essential for mutagenic activity.
Subject
Developmental Biology,Endocrinology,Genetics,General Materials Science,Molecular Biology,Animal Science and Zoology,Reproductive Medicine,General Medicine,Biotechnology
Cited by
19 articles.
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