Author:
Hungerford Natasha L.,Sands Donald P. A.,Kitching William
Abstract
The structures of a number of compounds isolated from the stems of
Tinospora smilacina (known as ‘snakevine’)
have been determined. The known clerodane-type compound columbin is a major
component, and two new minor compounds incorporate a heavily oxygenated
tetrahydrofuran ring in place of the furan ring of columbin. The lignan
isolariciresinol is also shown to be a minor component, along with
dihydrosyringenin. The traditional medicinal use of the vine, particularly in
countering snake venom, may be associated primarily with the presence of
columbin.
Cited by
22 articles.
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