Equine metabolic syndrome: evolution of understanding over two decades: a personal perspective

Abstract

There has been a marked increase in the incidence of equine obesity globally, especially in countries where there has been a shift away from the horse having an economically essential working role. This change in its core role, plus the increasing numbers of individual horse owners without access to traditional knowledge of animal and land management, have helped fuel this equine obesity ‘epidemic’. Other important potential contributory factors include increased availability of good grazing and/or forage, as well as supplementary feeds. Obesity now presents a major welfare issue for horses and ponies, not only because of the direct weight-associated effects, but also due to the increased risk it poses for certain clinical conditions, in particular laminitis. For many owners and veterinarians, obesity and the equine metabolic syndrome are synonymous, but this is not necessarily the case. Furthermore, as we understand more about this syndrome and the causes of endocrinopathic laminitis, the emphasis has shifted from tissue or peripheral insulin resistance to insulin dysregulation. The present paper outlines how our knowledge of equine metabolic syndrome arose and continues to develop, as well as the authors’ personal involvement in some of these advances.