Author:
Langler Richard F.,Paddock Robert L.,Thompson David B.,Crandall Ian,Ciach Michelle,Kain Kevin C.
Abstract
The synthesis and biological testing of a series of sulfonyl phenols and sulfonyl aryl methyl ethers has revealed that p-methoxyphenyl p-toluenesulfonate is a very selective and effective antimalarial agent which shows pronounced activity against human skin cancer cells. Application of a counter-attack strategy permits the direct preparation of the requisite tosylate ether from the bis(tosylate) of dihydroquinone.
Cited by
27 articles.
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