Author:
Deady Leslie W.,Loria Paul M.,Rodemann Thomas
Abstract
The reaction of the isocoumarin derivative
1-acetylimino-3-methyl-1H-2-benzopyran-4-carbonitrile
(1a) with aromatic ortho diamines provides entry to the
benzimidazo[2,1-a]isoquinoline and related
systems. Various conversions of the methyl and cyano groups in the tetracycles
into amide, aldehyde and acid functions have been carried out, along with
studies of electrophilic nitration.
Cited by
21 articles.
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