Author:
Collins DJ,Hetherington JW,Swan JM
Abstract
The reaction of diethyl
3-bromopropylphosphonate with phosphorus pentachloride
in carbon tetrachloride gave ethyl 3-bromopropylphosphonochloridate, which upon
reaction with anhydrous methylamine at -15� gave ethyl N-methyl-P-3-bromopropylphosphonamidate.
Treatment of this phosphonamidate with sodium hydride
in boiling xylene gave 2-ethoxy-1-methyl-l,2-azaphospholidine 2-oxide. Some
other possible routes to this compound were investigated.
Cited by
25 articles.
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