Regioselective Addition of 1,3-Dicarbonyl Dianions to Carbonyl Compounds: One Pot Lactonization and Ketalization of δ-Hydroxy-β-keto Esters to Protected Pyrone Derivatives-Reference-Cited by-同舟云学术

Regioselective Addition of 1,3-Dicarbonyl Dianions to Carbonyl Compounds: One Pot Lactonization and Ketalization of δ-Hydroxy-β-keto Esters to Protected Pyrone Derivatives

Published:2012 Issue:9 Volume:65 Page:1262
ISSN:0004-9425
Container-title:Australian Journal of Chemistry
language:en
Short-container-title:Aust. J. Chem.

Author:

Ghorai Manas K.,Halder Sandipan,Samanta Sauvik

Abstract

A simple and efficient strategy for the synthesis of 6-substituted-2-pyrone derivatives, by BF3·OEt2 mediated one pot cyclization and keto-protection of δ-hydroxy-β-keto esters, obtained via regioselective addition of 1,3-dicarbonyl dianion of ethyl acetoacetate to aldehydes and ketones is described.

Publisher

CSIRO Publishing

Subject

General Chemistry

Link

https://www.publish.csiro.au/CH/pdf/CH12062

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