Abstract
The reduction of
2-methoxy-1-naphthoic acids (1) with 2.4 equiv. of sodium in liquid ammonia
leads to the formation of the 1,4-dihydro compounds (2). These reduction
products on esterification with diazomethane followed by hydrolysis with dilute
mineral acids yield methyl 2-oxotetralin-1-carboxylates (5). This constitutes a
satisfactory general method of synthesis of (5).
Cited by
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