Chemoselective Activation Strategies of Amidic Carbonyls towards Nucleophilic Reagents

Author:

Pace Vittorio,Holzer Wolfgang

Abstract

Important advancements have been made in recent years in the development of chemoselective additions of nucleophiles to well known inert amide carbonyls in the presence of multi-electrophilic substrates. Herein, we present the most relevant results showing how carbonyl amides can be chemoselectively functionalised in the presence of electrophilic functionalities such as Weinreb amides.

Publisher

CSIRO Publishing

Subject

General Chemistry

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