Unprecedented increase in syphilis cases among heterosexual men and women in Japan, 2021–2022

Author:

Kasamatsu AyuORCID,Takahashi Takuri,Arima YuzoORCID,Otsuka Miyako,Arashiro Takeshi,Ito Hanae,Tabata Sakiko,Yamagishi TakuyaORCID,Suzuki Motoi

Abstract

Based on national surveillance data, we describe an unprecedented increase in syphilis case reports in Japan, with a surge in 2021–2022 reaching 10 141 cases in Week 42, 2022, a 1.7-fold increase over the same period in 2021. This already represented the highest annual case count in nearly half a century; by Week 52, 2022, the number reached 12 966, far surpassing the 7978 cases in 2021. Predominantly affecting heterosexual men and young women, the proportionate increase in primary and secondary syphilis cases suggests a true increase in incidence. The syphilis surge during the pandemic poses a serious public health concern and underscores the importance of adequate testing and preventive measures.

Funder

Ministry of Health, Labour and Welfare

Publisher

CSIRO Publishing

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health

Reference8 articles.

1. National Institute of Infectious Diseases. Reporting criteria for syphilis. Infectious Agents Surveillance Report; 2015. Available at [cited 11 October 2022].

2. National Institute of Infectious Diseases. Infectious disease weekly report week 42; 2022. Available at [cited 7 November 2022].

3. Molecular typing and macrolide resistance analyses of in heterosexuals and men who have sex with men in Japan, 2017.;J Clin Microbiol,2019

4. Rapid increase in reports of syphilis associated with men who have sex with women and women who have sex with men, Japan, 2012 to 2016.;Sex Transm Dis,2018

5. Ministry of Health Labour and Welfare. Vital statistics. Available at [cited 7 April 2023].

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