Author:
Ooi Hua Chee,Marcuccio Sebastian M.,Jackson W. Roy
Abstract
A synthesis of N-acetyl-4-deoxyneuraminic acid (11) from
N-acetylneuraminic acid (1) via the corresponding
unsaturated derivative (4) is described. This synthesis of the important
N-acetylneuraminic acid aldolase (EC 4.1.3.3) inhibitor
overcomes several difficulties associated with two previously published
syntheses.
Cited by
4 articles.
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