The synthesis and biological activity of (±)-(1α,2α,8α)-Indolizidine-1,2-diol-Reference-Cited by-同舟云学术

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The synthesis and biological activity of (±)-(1α,2α,8α)-Indolizidine-1,2-diol

Published:1984 Issue:7 Volume:37 Page:1503
ISSN:0004-9425
Container-title:Australian Journal of Chemistry
language:en
Short-container-title:Aust. J. Chem.

Author:

Colegate SM,Dorling PR,Huxtable CR

Abstract

The racemic indolizidine-1,2-dio1 (6) was synthesized and found to be a weak, in vitro inhibitor of acid α-D-mannosidase (Km 0.75 × 10-2) and acid α-D-glucosidase (Km 1.1 × 10-2 M).

Publisher

CSIRO Publishing

Subject

General Chemistry

Link

http://www.publish.csiro.au/CH/pdf/CH9841503

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