Author:
Hung TV,Mooney BA,Prager RH,Tippett JM
Abstract
The lithiation
of methoxy- and methylenedioxy-bemyl alcohols is
described; subsequent reactions with ethyl chloroformate
and carbon dioxide to form phthalides have been
investigated, and are compared with metallation-carboxylation
of alternative substrates. The preparation of phthalideisoquinoline
analogues by this method proceeds only in low yields due to the acidity of the
benzylic position in the benzylisoquinoline
precursor.
Cited by
46 articles.
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