Clathriol B, a New 14β Marine Sterol from the New Zealand Sponge Clathria lissosclera

Abstract

A new anti-inflammatory sterol, clathriol B (1.3 mg), was isolated from the New Zealand marine sponge Clathria lissosclera collected at the Three Kings Islands. Clathriol B possesses the unusual 14β stereochemistry, a structural feature that occurs naturally only in marine sponges.