Abstract
The o-nitrophenylthio
derivative of 2-methylalanine served as the precursor of several new ester
hydrochlorides, which have been investigated as intermediates for the synthesis
of peptides containing this amino acid. Particular consideration is given to the
effect of the steric hindrance associated with 2-methylalanine. Synthesis of a
2- methylalanyl analogue of the opiate agonist leucine-enkephalin is described.
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6 articles.
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