Abstract
The synthesis of several
new N,N?-dialkyl barbituric acids is reported. The compounds are the diethyl derivatives
of pentobarbital and amobarbital, and the bis(chloroethyl) derivatives of
pentobarbital, amobarbital and phenobarbital. Separation and isolation of mono-
and di-methyl, mono- and diethyl derivatives of the
three barbituric acids are also described. Infrared, mass and N.M.R. spectral data
are given.��� Of the derivatives, only the methylated
compounds are significantly more volatile than the parent acids.
Cited by
12 articles.
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