Abstract
A number of 1,8-naphthyridines
including 8-aza analogues of chloroquine and amodiaquine,
and similar 1,8-naphthyridines with 2- and 7-methyl substituents have been
prepared. These compounds showed minimal antimalarial activity in a preliminary
in vivo screen against Plasmodium vinckei vinckei.
Cited by
42 articles.
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1. Synthesis and characterization of some new thieno[2,3-b]pyridines, thieno[2,3-c][2,7]naphthyridinones and pyrazolo[3,4-c][2,7]naphthyridinones with expected biological activity;Arkivoc;2024-06-03
2. NorA, Tet(K), MepA, and MsrA Efflux Pumps in Staphylococcus aureus, their Inhibitors
and 1,8-Naphthyridine Sulfonamides;Current Pharmaceutical Design;2023-02
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4. Study of antifungal activity of 2-Methyl-3-(5'-aryl/aryloxymethyl-1', 3', 4'-oxadiazol-2'-yl) amino-1, 8-naphthyridines;Research Journal of Pharmacy and Technology;2022-02-26
5. Design, Synthesis and Biological Evaluation of Tetrahydrodibenzo[b,g][1,8]napthyridinones as Potential Anticancer Agents and Novel Aurora Kinases Inhibitors;ChemistrySelect;2021-04-14