RISK FACTORS FOR THE DEVELOPMENT OF NOSOCOMIAL PNEUMONIA AFTER AORTIC ARCH SURGERY

Abstract

HighlightsFor the first time, the incidence and timing of the development of postoperative pneumonia in patients undergoing surgical reconstruction of the aortic arch in the post-covid period were studied. Risk factors for pneumonia and predictors of the severe course of the disease in this cohort of patients were identified. The results obtained will make it possible to differentiate patients at risk of developing pneumonia from the general population of patients undergoing surgical reconstruction of the aortic arch for targeted perioperative prevention of this complication. AbstractAim. To study the incidence of nosocomial pneumonia (NP) after aortic arch surgery, and to determine the impact of perioperative factors on the risk for its development and severity of its course.Methods. A retrospective analysis of 66 case histories of patients who underwent aortic arch surgery in 2022 was carried out. The incidence and timing of the development of pneumonia were revealed, the severity of its course was assessed. The impact of the main demographic, clinical, perioperative factors on the risk for the pneumonia development and the severity of its course was studied.Results. The incidence of pneumonia after aortic arch surgery was 24.2%. A relationship between smoking (OR 1.17; 95% CI [0.23; 1.43], p = 0.007), smoking index (OR 0.99; 95% CI [0.92; 1.07], p = 0.002) and the risk of NP developing as well as between the duration of mechanical ventilation and the severity of NP was found with a univariate logistic regression analysis (OR 1.26; 95% CI [1.0; 1.59], p = 0.049).Conclusion. The risk for NP development in patients who underwent thoracic aortic surgery is associated with smoking and smoking intensity in the preoperative period. The predictor of the severe course of NP is the duration of mechanical ventilation.