Author:
Chaley M.B.,Tyulko Zh.S.,Kutyrkin V.A.
Abstract
Method recognizing the flavivirus species, including a subtype recognition, that based on the genome sequence analysis, is proposed. This method takes into consideration frequency characteristics of amino acid codons in the coding sequences of full-length polyprotein of flavivirus genomes. High reliability of the method is proved in recognizing flavivirus genomes from 15 groups of different species and sub-types, that are sufficiently represented in the GenBank database. Ten various species of the flaviviruses, four sub-types of Dengue virus and Kunjin virus, that is suggested to be a sub-type of West Nile virus, are considered in the work.
Publisher
Institute of Mathematical Problems of Biology of RAS (IMPB RAS)
Subject
Applied Mathematics,Biomedical Engineering
Cited by
5 articles.
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