Mucoepidermoid carcinoma of the trachea in a 9-year-old male child: case report and review of literature

Author:

Uppal Deepak Kumar,Madan Renu,Peters Nitin J.,Bal Amanjit,Ballari Nagarjun,Goyal Shikha,Khosla Divya

Abstract

Mucoepidermoid carcinoma (MEC) is most common malignancy of minor salivary glands in adults. Pulmonary MEC is extremely uncommon comprising of only 0.1%–0.2% of the primary lung malignancies and <1% of primary bronchial tumors. It is even rarer in children and literature limited to few case reports only. Here we present a case report of a 9-year-old boy diagnosed with primary MEC of trachea along with review of the literature. A 9-year-old male child presented with complaint of dry cough for two years which was later associated with shortness of breath after one year. Bronchoscopic examination revealed a growth arising from right lateral wall of carina occluding 50% of the lumen and detailed histopathological examination revealed it to be a MEC of the trachea. Patient underwent local excision of the tumor with primary anastomosis. In view of positive margins adjuvant radiotherapy of 60 Gy in 30 fractions were given to the tumor bed. Patient tolerated the treatment well and is disease free at 6 months follow-up. Experience with MEC of the trachea in children is limited and optimal treatment protocols have not been defined, with current treatment mainly extrapolated from MEC of the salivary glands.

Publisher

Korean Society for Therapeutic Radiology and Oncology

Subject

Radiology, Nuclear Medicine and imaging,Oncology

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Pulmonary mucoepidermoid carcinoma in a 7‐year‐old child;Pediatric Pulmonology;2024-01-15

2. Molecular Mechanisms of Carcinogenesis in Pediatric Airways Tumors;International Journal of Molecular Sciences;2023-01-22

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