CLINICAL AND MORPHOLOGICAL FEATURES OF ACUTE AND CHRONIC WOUNDS

Abstract

Background. The chronicity of the wound is a factor leading to a greater number of postoperative complications when performing plastic closure of wound defects and requires the use of special methods of preoperative preparation. In clinical practice, it is important to use precise clinical and morphological criteria to assess the activity of the inflammatory response and the degree of impairment of the proliferative phase of the reparative process. Aim. To determine the features of clinical parameters of the local status of wound defects and their correspondence to morphological criteria in patients with acute and chronic wounds of various genesis. Material and Methods. Clinical signs of acute and chronic wounds in 26 patients with different types and duration of integumentary tissue defects were described. In a hospital setting, a morphological study of the biopsy specimens from wounds and surrounding tissues was performed to identify histological signs of chronic wound healing. The correspondence between clinical and morphological signs of acute and chronic wounds was analyzed. Results. The initial study of the local status of wound defects did not reveal significant differences in the clinical signs of acute and chronic wounds. Histological examination of the wound biopsy specimens revealed morphological signs of chronic wound healing. Conclusion. Evaluation of clinical signs of the local wound status is necessary to identify the dynamics of wound parameters during treatment. Histological examination of wound biopsy specimens makes it possible to more reliably identify signs of chronicity of the wound.