1. Hospital for Special Surgery, 535 E 70th Street, New York, NY 10021 USA; Biophysics and Systems Biology, Weill Medical College and Graduate School of Cornell University, 1300 York Avenue, New York, NY 10021 USA, USA; Sibley School of Aerospace and Mechanical Engineering, Cornell University, 219 Upson Hall, Ithaca, NY 14853, USA