The prehistory of mycotoxins: related cases from ancient times to the discovery of aflatoxins

Author:

Ramos A.1,Sanchis V.1,Marín S.1

Affiliation:

1. Department of Food Technology, Applied Mycology Unit, University of Lleida, XaRTA-UTPV, Av. Rovira Roure 191, 25198 Lleida, Spain

Abstract

This paper presents a journey through the known and the presumed history of two important mycotoxicoses which played an important role in the history of mankind before aflatoxins were discovered: (1) ergotism, also known as St. Anthony's fire or Holy Fire, linked to the consumption of cereals (especially rye) contaminated by the hallucinogenic and vasoconstrictor alkaloids produced by the Claviceps purpurea ergot, whose presence in Europe during the Middle Ages was considered epidemic, and (2) the so-called alimentary toxic aleukia (also known by its English acronym ATA), caused by the trichothecenes produced by Fusarium sporotrichioides and Fusarium poae, which devastated a large part of Russia shortly before the characterisation of the toxins of Aspergillus flavus.

Publisher

Wageningen Academic Publishers

Subject

Public Health, Environmental and Occupational Health,Toxicology,Food Science

Reference70 articles.

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