Affiliation:
1. SI “The Institute of Traumatology and Orthopedics of the National Academy of Medical Sciences of Ukraine”. Kyiv, Ukraine
Abstract
Abstract. The authors of the paper analyzed the experience of domestic and foreign experts on the effi-ciency of HA preparation in big joint osteoarthritis management. Task of the study is to analyze literature sources to identify the efficiency of HA preparations in big joints osteoarthritis management. Materials and methods: articles published by specialized scientific journals, paper collections, internet sources. Results: The analysis of literature sources determined the essential role of HA in joint cartilage nutrition and function. The researches tend to believe that an ideal HA preparation must be as close as possible to the physiological HA of joint’s synovial fluid. The HA preparation elaborated in our state, Artropatch meets these demands completely. Conclusions. Modern HA injectable preparations are expedient on the 1-3 stage of OA. Anti-inflammatory effect of HA preparations predetermines the possibility to decrease the intake dose and period of non-steroid anti-inflammatory drugs, consequently decreasing the risk of many unfavorable side effects of NSAIPs. The high safety level of HA preparations and no significant side effects after long-term treatment make them widely used in clinical practice of modern orthopedic surgeons.
Publisher
Pan-Ukrainian Association of Traumatology and Osteosynthesis
Reference39 articles.
1. International comparative evaluation of fixed-bearing non-posterior-stabilized and posterior-stabilized total knee replacements / Comfort T., Baste V., Froufe M. A. [et al.] // J. Bone Joint Surg. Am. – 2014. – Vol. 96, Suppl. 1. – P. 65-72. doi:10.2106/JBJS.N.00462
2. Progressing toward, and recovering from, knee replacement surgery: a five-year cohort study / Riddle D. L., Perera R. A., Stratford P. W. [et al.] // Arthritis Rheum. – 2013. – Vol. 65, № 12. – P. 3304-3313. . doi:10.1002/art.38139
3. Reliability of the hip-to-ankle radiograph in determining the knee and implant alignment after total knee arthroplasty / Skyttä E.T., Haapamäki V., Koivikko M., Huhtala H., Remes V.// Acta Orthop. Belg. – 2011. – Vol. 77. – P. 329-335. PMID: 21846000
4. Насонова В.А. Ревматические болезни в России в начале XXI века. / В.А. Насонова, О.М. Фоло-меева, Ш.Ф. Эрдес // Научно-практ. ревматол. 2003. – №. – 6-10.
5. Гайко Г.В. Сучасні підходи до профілактики та лікування остеоартрозу / Г.В. Гайко, А.Т. Бруско // Літопис травматології та ортопедії. – 2008. – № 1 – 2. – С. 157¬-160.