Renal transplant sonrası iki yıllık izlemde gelişen üriner sistem enfeksiyonlarının değerlendirilmesi: Tek merkez deneyimi

Author:

SARI Tugba1,DURSUN Belda1,ÇERİ Mevlüt1,TURGUT Hüseyin1,ÖZBAN Murat1

Affiliation:

1. PAMUKKALE ÜNİVERSİTESİ, TIP FAKÜLTESİ

Abstract

Introduction:After renal transplantation, urinary tract infection (UTI) is observed in 23-75% of cases. In this study, we aimed to investigate the incidence of UTIs after renal transplantation, the causative pathogens and the predisposing factors that increase the risk. Methodology: Patients who underwent renal transplantation in our hospital between 2016-2017 were included in the study. Results: Twenty-five patients who underwent kidney transplantation were included in the study. UTI was detected in 12 patients (48%). One patient had neurogenic bladder, three had nephrolithiasis and one had vesicoureteral reflux. 8 of the patients had at least two UTI attacks. In total 38 UTI attacks; There were 7 (18.4%) nitrite positivity. UTI was detected in 15 (39.5%) patients during the first 3 months after transplantation. While 7 (18.4%) of the urine cultures were gram positive and 27 (71.1%) were gram negative bacteria, 4 (10.5%) were found as contamination. Escherichia coli (34.2%) was the most common causative agent, followed by Klebsiella pneumoniae (21.1%), Enterococcus faecium (18.4%), Pseudomonas aeruginosa (5.3%) and other gram negative (%). 10.5) uropathogens were found to be followed. When compared with basal and UTI GFR (glomerular filtration rate) levels, the GFR values detected during UTI were decreased significantly (p = 0.00). The most frequently preferred antibiotics in UTI treatment were ertapenem 42.1%, levofloxacin 10.5%, seftriaxon 10.5% and fosfomycin 10.5%. Discussion: Improperly treated UTI negatively affects the outcome of transplantation and increases mortality. Therefore, risk factors, antibiotic resistance and empirical treatments should be reviewed and treatment success should be increased.

Publisher

Pamukkale University

Subject

General Medicine

Reference30 articles.

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