Takotsubo Kardiyomiyopati Üzerine Klinik Deneyimimiz ve Vaka Serimiz

Abstract

Objective In this study we aimed to evaluate the clinical course and prognosis of Takotsubo Cardiomyopathy cases diagnosed and treated in our clinic. Cases Takotsubo Cardiomyopathy was first described in 1990 by Hikaru Sato et al. The reason why it is called Tako-tsubo cardiomyopathy; This is due to the appearance of the left ventricle resembling the narrow-necked, broad-bottomed container used by Japanese fishermen to catch octopuses. In addition to Takotsubo cardiomyopathy, this syndrome is also called ampulla cardiomyopathy, Human stress cardiomyopathy and Broken heart syndrome. In this study, a series of 7 cases of Takotsubo Cardiomyopathy diagnosed and treated in our clinic are presented and the clinical course and prognosis of the disease are examined. Results The age range of the series, consisting of six female and one male patients, ranged from 57 to 81 years (median age 70). All of the female patients were in the postmenopausal period and physical or emotional stress was found in four of them. Moderate-to-moderate cardiac enzyme elevation was found in all of the patients. While noncritical plaques were detected in the angiography of six patients who underwent coronary angiography and ventriculography, one patient had normal coronaries. During the follow-up, in-hospital death due to non-cardiac causes (Acute Myeloblastic Leukemia) was observed in one of the patients. In the echocardiographic follow-up of six surviving patients, it was observed that the LV ejection fraction was normalized and ballooning regressed within two months. Conclusion The awareness of Takotsubo Cardiomyopathy among cardiology physicians in the world and in our country is increasing. However, information about its prevalence, clinical course and short-term prognosis in our country is insufficient. In the study, a new series was presented in addition to the first data of our country. It is thought that there may be some different physical risk factors that have not yet been identified.