Christian Raetz: Scientist and Friend Extraordinaire

Author:

Dowhan William1,Nikaido Hiroshi2,Stubbe JoAnne3,Kozarich John W.4,Wickner William T.5,Russell David W.6,Garrett Teresa A.7,Brozek Kathryn8,Modrich Paul9

Affiliation:

1. Department of Biochemistry and Molecular Biology and Center for Membrane Biology, University of Texas Medical School, Houston, Texas 77030;

2. Department of Molecular and Cell Biology, University of California, Berkeley, California 94720;

3. Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139;

4. ActivX Biosciences Inc., La Jolla, California 92037;

5. Department of Biochemistry, Dartmouth Medical School, Hanover, New Hampshire 03755;

6. Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, Texas 75390;

7. Department of Chemistry, Vassar College, Poughkeepsie, New York 12604;

8. American School of Paris, Saint-Cloud, France 92210;

9. Department of Biochemistry and Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina 27710;

Abstract

Chris Raetz passed away on August 16, 2011, still at the height of his productive years. His seminal contributions to biomedical research were in the genetics, biochemistry, and structural biology of phospholipid and lipid A biosynthesis in Escherichia coli and other gram-negative bacteria. He defined the catalytic properties and structures of many of the enzymes responsible for the “Raetz pathway for lipid A biosynthesis.” His deep understanding of chemistry, coupled with knowledge of medicine, biochemistry, genetics, and structural biology, formed the underpinnings for his contributions to the lipid field. He displayed an intense passion for science and a broad interest that came from a strong commitment to curiosity-driven research, a commitment he imparted to his mentees and colleagues. What follows is a testament to both Chris's science and humanity from his friends and colleagues.

Publisher

Annual Reviews

Subject

Biochemistry

Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Eugene P. Kennedy’s Legacy: Defining Bacterial Phospholipid Pathways and Function;Frontiers in Molecular Biosciences;2021-03-25

2. Understanding phospholipid function: Why are there so many lipids?;Journal of Biological Chemistry;2017-06

3. The role of atypical ubiquitination in cell regulation;Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry;2017-01

4. Lipids and Extracellular Materials;Annual Review of Biochemistry;2014-06-02

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