Common Cardiovascular Complications of Cancer Therapy: Epidemiology, Risk Prediction, and Prevention

Author:

Narayan Vivek12,Ky Bonnie324

Affiliation:

1. Division of Hematology/Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104;

2. Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania 19104

3. Division of Cardiology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104;

4. Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania 19104

Abstract

There is growing awareness of the overlap between oncologic and cardiovascular (CV) diseases, including a wide range of CV effects of anticancer therapies. As novel anticancer therapeutics become available and cancer survival outcomes improve, the CV implications of cancer therapy become increasingly important. In addition to outlining the CV effects of commonly used cancer therapies and their consequences for long-term survivorship, this review highlights the recent efforts to improve the risk prediction and prevention of CV toxicity through the evaluation of sensitive measures for early toxicity detection and the implementation of cardioprotective strategies.

Publisher

Annual Reviews

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

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