Applied Animal Genomics: Results from the Field

Author:

Van Eenennaam Alison L.1,Weigel Kent A.2,Young Amy E.1,Cleveland Matthew A.3,Dekkers Jack C.M.4

Affiliation:

1. Department of Animal Science, University of California, Davis, California 95616;,

2. Department of Dairy Science, University of Wisconsin, Madison, Wisconsin 53706;

3. Genus plc, Hendersonville, Tennessee 37075;

4. Department of Animal Science, Iowa State University, Ames, Iowa 50011;

Abstract

Genomic selection (GS) is the use of statistical methods to estimate the genetic merit of a genotyped animal based on prediction equations derived from large ancestral populations with both phenotypes and genotypes. It has revolutionized the dairy cattle breeding industry and has been implemented with varying degrees of success in other animal breeding programs, including swine, poultry, and beef cattle. The findings of empirical field studies applying GS to the breeding sectors of these main animal protein industries are reviewed. Several translational considerations must be addressed before implementing GS in genetic improvement programs. These include determining and obtaining economically relevant phenotypes and determining the optimal size of the training population, cost-effective genotyping strategies, the practicality of field implementation, and the relative costs versus the benefits of the realized rate of genetic gain. GS may additionally change the optimal breeding scheme design, and studies that address this consideration are also reviewed briefly.

Publisher

Annual Reviews

Subject

General Veterinary,Genetics,Animal Science and Zoology,Biotechnology

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