1. Department of Physiology and Biophysics and Zilkha Neurogenetic Institute, University of Southern California, Los Angeles, California 90033;
2. Department of Internal Medicine and Center on Aging, University of Utah Health Sciences Center, Department of Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah 84148;
3. Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205;