Chemoprevention of Prostate Cancer-Reference-Cited by-同舟云学术

Chemoprevention of Prostate Cancer

Published:2014-01-14 Issue:1 Volume:65 Page:111-123
ISSN:0066-4219
Container-title:Annual Review of Medicine
language:en
Short-container-title:Annu. Rev. Med.

Author:

Vemana Goutham¹,Hamilton Robert J.²,Andriole Gerald L.¹,Freedland Stephen J.³⁴⁵

Affiliation:

1. Division of Urologic Surgery, Washington University School of Medicine in St. Louis, Siteman Cancer Center, St. Louis, Missouri;

2. Division of Urology, Department of Surgery, University of Toronto, Toronto M5G 2M9, Ontario, Canada;

3. Surgery Section, Durham VA Medical Center, Durham, North Carolina 27710

4. Duke Prostate Center, Division of Urology, Department of Surgery, Duke University School of Medicine, Durham, North Carolina 27710

5. Department of Pathology, Duke University School of Medicine, Durham, North Carolina 27710;

Abstract

Large prospective randomized trials, such as the Prostate Cancer Prevention Trial (PCPT), Reduction by Dutasteride of Prostate Cancer Events (REDUCE) trial, and Selenium and Vitamin E Cancer Prevention Trial (SELECT), have provided practitioners with considerable data regarding methods of treatment and prevention of prostate cancer. The best-studied medications for prevention are 5 alpha-reductase inhibitors. Their efficacy and side effects are well characterized. Other medications, dietary nutrients, and supplements have not been as well studied and generally do not demonstrate efficacy for disease prevention with an acceptable level of evidence.

Publisher

Annual Reviews

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

https://www.annualreviews.org/doi/pdf/10.1146/annurev-med-121211-091759

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1. Phase I Trial of Encapsulated Rapamycin in Patients with Prostate Cancer Under Active Surveillance to Prevent Progression;Cancer Prevention Research;2021-01-29

2. Long-term use of 5-alpha-reductase inhibitors is safe and effective in men on active surveillance for prostate cancer;Prostate Cancer and Prostatic Diseases;2020-03-09

3. ProDiet: A Phase II Randomized Placebo-controlled Trial of Green Tea Catechins and Lycopene in Men at Increased Risk of Prostate Cancer;Cancer Prevention Research;2018-10-11

4. Repurposing existing medications in oncology and their potential role in oral cancer;Oral Diseases;2018-06-07

5. Homology Modeling of 5-alpha-Reductase 2 Using Available Experimental Data;Interdisciplinary Sciences: Computational Life Sciences;2018-01-30