PROGNOSIS IN CRITICAL CARE

Author:

Ohno-Machado Lucila1,Resnic Frederic S.1,Matheny Michael E.1

Affiliation:

1. Decision Systems Group, Department of Radiology; 2Division of Cardiology, Department of Medicine; and 3Division of General Internal Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115; 4Division of Health Sciences and Technology, Harvard-MIT, Cambridge, Massachusetts 02139

Abstract

Prognostic risk prediction models have been employed in the intensive care unit (ICU) setting since the 1980s and provide health care providers with important information to help inform decisions related to treatment and prognosis, as well as to compare outcomes across institutions. Prognostic models for critical care are among the most widely utilized and tested predictive models in healthcare. In this article, we review and compare mortality prediction models, including the APACHE (1981), SAPS (1984), APACHE-II (1985), MPM (1987), APACHE-III (1991), SAPS-II (1993), and MPM-II (1993). We emphasize the importance of model calibration in this domain. In addition, we present a brief review of the statistical methodology, multiple logistic regression, which underlies most of the models currently used in critical care.

Publisher

Annual Reviews

Subject

Biomedical Engineering,Medicine (miscellaneous)

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