1. The James Hogg iCAPTURE Center for Cardiovascular and Pulmonary Research, St. Paul's Hospital, Providence Health Care Research Institute, Department of Pathology & Laboratory Medicine, University of British Columbia, Vancouver V6Z 1Y6, Canada;
2. Child & Family Research Institute, Department of Cardiovascular Sciences, and Department of Anesthesiology, Pharmacology, and Therapeutics, University of British Columbia, Vancouver V5Z 4H4, Canada;