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New DNA Sequencing Methods

Published:2001-08 Issue:1 Volume:3 Page:195-223
ISSN:1523-9829
Container-title:Annual Review of Biomedical Engineering
language:en
Short-container-title:Annu. Rev. Biomed. Eng.

Author:

Marziali Andre¹²,Akeson Mark¹²

Affiliation:

1. Department of Physics and Astronomy, University of British Columbia, 6224 Agricultural Road, Vancouver, BC, Canada, V6T-1Z1;

2. Department of Chemistry and Biochemistry, University of California, Santa Cruz, California 95064;

Abstract

▪ Abstract The Human Genome Project and other major genomic sequencing projects have pushed the development of sequencing technology. In the past six years alone, instrument throughput has increased 15-fold. New technologies are now on the horizon that could yield massive increases in our capacity for de novo DNA sequencing. This review presents a summary of state-of-the-art technologies for genomic sequencing and describes technologies that may be candidates for the next generation of DNA sequencing instruments.

Publisher

Annual Reviews

Subject

Biomedical Engineering,Medicine (miscellaneous)

Link

https://www.annualreviews.org/doi/pdf/10.1146/annurev.bioeng.3.1.195

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