Multifunctional 3D platforms for rapid hemostasis and wound healing: Structural and functional prospects at biointerfaces
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Published:2022-11-29
Issue:1
Volume:9
Page:
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ISSN:2424-8002
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Container-title:International Journal of Bioprinting
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language:
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Short-container-title:Int J Bioprint
Author:
Ganguly Keya,Espinal Maria Mercedes,Deb Dutta Sayan,K. Patel Dinesh,V. Patil Tejal,Luthfikasari Rachmi,Lim Ki-Taek
Abstract
Fabrication of multifunctional hemostats is indispensable against chronic blood loss and accelerated wound healing. Various hemostatic materials that aid wound repair or rapid tissue regeneration has been developed in the last 5 years. This review provides an overview of the three-dimensional (3D) hemostatic platforms designed through the latest technologies like electrospinning, 3D printing, and lithography, solely or in combination, for application in rapid wound healing. We critically discuss the pivotal role of micro/nano-3D topography and biomaterial properties in mediating rapid blood clots and healing at the hemostat-biointerface. We also highlight the advantages and limitations of the designed 3D hemostats. We anticipate that this review will guide the fabrication of smart hemostats of the future for tissue engineering applications.
Publisher
Whioce Publishing Pte Ltd
Subject
Industrial and Manufacturing Engineering,Materials Science (miscellaneous),Biotechnology
Cited by
2 articles.
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