Comparison of efficacy of Ketorolac %0.4 and Dexamethasone %0.1 in inflamed Pterygium and Pinguecula

Abstract

Objective: This study investigated the effect of the ketorolac %0.4 and dexamethasone %0.1 on suppressing symptoms in inflamed pterygium and pinguecula. Methods: 50 patients were included in the study. The patients were divided into two groups, each consisting of 25 patients. Ketorolac %0.4 eye drops were dropped in group 1, and dexamethasone %0.1 eye drops were started in group 2. Groups were compared 3,7,14,30,45. days in terms of total signs and symptoms. Results: After 14 days of drug administration group 1, scores were reduced %85 for total signs (2.52+1.16, p=0.001), %86 for total symptoms (4.10+2.61, p=0.001) and total scores showed a significant reduction of %86 (6.62+2.91, p=0.001) for the score. After 14 days of drug administration in group 2, scores were reduced %85 for total signs (2.70+1.46, p=0.001), %86 for total symptoms (4.25+2.36, p=0.001), and total scores showed a significant reduction of %86 (7.10+2.99, p=0.001) for the score. The scores for each sign and symptom decreased during the study. However, the statistical evaluation of each sign and symptom was similar in groups 1 and 2. There was no difference between groups 1 and 2 for total signs, total symptoms, and total score on days 3,7 and 14. No significant difference was found between groups 1 and 2 for total signs, total symptoms, and total score on days 14,30 and 45 (p>0.05). Conclusion: Current study revealed that topical ketorolac %0.4 solutions are as effective as dexamethasone in treating inflammatory pterygium and pinguecula. We suggest that it can be used alone to treat this disease. We need more studies to support our work.