Canine pyoderma histopathology: Insights and findings

Abstract

Pyoderma is a common bacterial skin infection in canines, resulting from a complex interplay between host immunity, environmental factors and genetic predisposition. This study investigated the dermatopathological changes associated with canine pyoderma and its therapeutic management. Thirty-four client-owned dogs with clinical signs that are suggestive of pyoderma were included. Punch biopsies of skin lesions were subjected to histopathological examination revealed extensive infiltration of inflammatory cells, including neutrophils, eosinophils, round cells and mast cells in the epidermis, dermis and subcutaneous tissue. Bacterial isolation and identification confirmed Staphylococcus spp., as the predominant causative agent, with occasional isolation of Pseudomonas spp., and Proteus spp. A higher incidence of pyoderma was reported in Labrador breeds and therapy was carried out as per ABST. The duration of therapy ranged from 14-28 days, tailored to the depth and extent of cellular infiltration.