Author:
RAHEEL R,ASHRAF M,JAVEED A,BASHIR R,MUNIR N,ALTAF I
Abstract
The present study was designed to determine the cytotoxic and antiviral potential of ethanolic extract of Acacia nilotica leaves, pods and bark against PPRV by using MTT [3–(4,5–dimethylthiazol–2-yl)–2,5-diphenylte- trazolium bromide] colorimetric assay. Antiviral property of ethanolic extract of leaves was higher as compared to pods and bark at its non-cytotoxic concentrations. This plant might be a good source to isolate effective antiviral agents against PPRV.
Publisher
Indian Council of Agricultural Research, Directorate of Knowledge Management in Agriculture
Subject
General Veterinary,Animal Science and Zoology
Reference9 articles.
1. Abubakar M, Ashiq S, Zahoor A B, Arshed M J and Banyard A C. 2011. Diagnosis and control strategies for peste des petits ruminants virus: Global and Pakistan perspectives. Pakistan Veterinary Journal 31: 267–74.
2. Hussain M, Irshad H and Khan M. 2008. Laboratory diagnosis of transboundary animal diseases in Pakistan. Transboundary and Emerging Diseases 55:190–95.
3. Isaian A, Pourpak Z, Nikfarjam L and Earhoudi A. 2003. Comparison of two proliferation assays MTT and ltt in immunodeficient patients. Iranian Journal of Allergy, Asthma and Immunology 2:111–114.
4. Ian Freshney R. 2011. Culture of Animal Cells: A Manual of Basic Technique and Specialized Applications. John Wiley and Sons.
5. Kalaivani T, Rajasekaran C and Mathew L. 2011. Free radical scavenging, cytotoxic, and hemolytic activities of an active antioxidant compound ethyl gallate from leaves of Acacia nilotica (L.) wild. Ex. Delile subsp. Indica (Benth.) Brenan. Journal of Food Science 76: T144–49.