Near-Infrared Spectroscopic Measurement of Lactate in Human Plasma-Reference-Cited by-同舟云学术

Near-Infrared Spectroscopic Measurement of Lactate in Human Plasma

Published:2000-02 Issue:2 Volume:54 Page:300-304
ISSN:0003-7028
Container-title:Applied Spectroscopy
language:en
Short-container-title:Appl Spectrosc

Author:

Lafrance Denis¹,Lands Larry C.¹,Hornby Laura¹,Burns David H.¹

Affiliation:

1. Department of Chemistry, McGill University, Montreal, Quebec H3A 2K6, Canada (D.L., D.H.B.); and Respiratory Medicine Department, McGill University Health Centre-Montreal Children's Hospital, Montreal, Quebec H3H 1P3, Canada (L.C.L., L.H.)

Abstract

A method based on near-infrared spectroscopy (NIRS) is presented, which provides a rapid analysis of lactate in plasma. In order to test the technique, NIRS analysis and enzymatic measurements were made on plasma samples taken from exercising humans. A correlation coefficient of 0.995 and a standard error of 0.51 mmol/L were found between the enzymatic and the NIR results. This standard error is within the range needed for real-time monitoring of lactate in plasma for exercising studies. In the future, this technique may provide a valuable tool to assess physiological status for research and clinical use.

Publisher

SAGE Publications

Subject

Spectroscopy,Instrumentation

Link

http://journals.sagepub.com/doi/pdf/10.1366/0003702001949267

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