Use of the Orthogonal Projection Approach (OPA) to Monitor Batch Processes-Reference-Cited by-同舟云学术

Use of the Orthogonal Projection Approach (OPA) to Monitor Batch Processes

Published:2003-01 Issue:1 Volume:57 Page:80-87
ISSN:0003-7028
Container-title:Applied Spectroscopy
language:en
Short-container-title:Appl Spectrosc

Author:

Gourvénec S.¹,Lamotte C.¹,Pestiaux P.¹,Massart D. L.¹

Affiliation:

1. ChemoAC, Pharmaceutical Institute, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussel, Belgium (S.G., D.L.M.); ATOFINA Research, Zone Industrielle, B-7181 Feluy, Belgium (C.L.); and TOTALFINAELF France, Centre de Recherche de Gonfreville, BP 27, 76700 Harfleur, France (P.P.)

Abstract

The orthogonal projection approach (OPA) and multivariate curve resolution (MCR) are presented as a way to monitor batch processes using spectroscopic data. Curve resolution allows one to look within a batch and predict on-line real concentration profiles of the different species appearing during reactions. Taking into account the variations of the process by using an augmented matrix of complete batches, the procedure explained here calculates some prediction coefficients that can afterwards be applied for a new batch.

Publisher

SAGE Publications

Subject

Spectroscopy,Instrumentation

Link

http://journals.sagepub.com/doi/pdf/10.1366/000370203321165241

Reference21 articles.

1. Control Procedures for Residuals Associated With Principal Component Analysis

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