In Vivo Raman Study of the Living Rat Esophagus and Stomach Using a Micro-Raman Probe under an Endoscope-Reference-Cited by-同舟云学术

In Vivo Raman Study of the Living Rat Esophagus and Stomach Using a Micro-Raman Probe under an Endoscope

Published:2007-06 Issue:6 Volume:61 Page:579-584
ISSN:0003-7028
Container-title:Applied Spectroscopy
language:en
Short-container-title:Appl Spectrosc

Author:

Hattori Yusuke¹,Komachi Yuichi¹,Asakura Toru¹,Shimosegawa Toru¹,Kanai Gen-Ichi¹,Tashiro Hideo¹,Sato Hidetoshi¹

Affiliation:

1. Optical Biopsy Development Research Unit, The Institute of Physical and Chemical Research (RIKEN), 2-1 Hirosawa, Wako-shi, 351-0198, Japan (Y.H., H.S.); Probing Technology Laboratory, The Institute of Physical and Chemical Research (RIKEN), 2-1 Hirosawa, Wako-shi, 351-0198, Japan (Y.K., H.T., H.S.); Machida Endoscope Co., Ltd., 6-13-8 Honkomagome, Tokyo, 113-0021, Japan (Y.K., G.-I.K.); Department of Food Nutritional Science, Miyagi Gakuin Women's University, 9-1-1 Aoba-ku, Sendai-shi, 981-8557, Japan (T...

Abstract

A small endoscope system equipped with a micro Raman probe is developed for in vivo Raman measurements in living rats. The measurements are done under anesthesia and artificial respiration to minimize the impact on the rats. Raman spectra of living rat esophagus and stomach are successfully measured. Our results suggest that the Raman spectra reflect subsurface tissue structure that cannot be distinguished in the endoscope image. After the experiments, rats recover without any aftereffects. It is verified that the Raman measurement using the present system is safe and noninvasive for rats.

Publisher

SAGE Publications

Subject

Spectroscopy,Instrumentation

Link

http://journals.sagepub.com/doi/pdf/10.1366/000370207781269747

Reference26 articles.

1. Tumour Production in Glandular Stomach of Rat by N-Methyl-N′-Nitro-N-Nitrosoguanidine

2. Effects in Rats of Sodium Chloride on Experimental Gastric Cancers Induced by N-Methyl-N′-nitro-N-nitrosoguanidine or 4-Nitroquinoline-1-oxide2

3. Vibrational spectroscopy for molecular characterisation and diagnosis of benign, premalignant and malignant skin tumours

Cited by 72 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Development of in-situ Raman diagnosis technique of eosinophil esophagitis;Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy;2023-01

2. In vivo spectroscopy: optical fiber probes for clinical applications;Expert Review of Medical Devices;2022-09-02

3. Raman Spectroscopy: A Novel Technology for Gastric Cancer Diagnosis;Frontiers in Bioengineering and Biotechnology;2022-03-15

4. Raman Imaging and Fluorescence Lifetime Imaging Microscopy for Diagnosis of Cancer State and Metabolic Monitoring;Cancers;2021-11-13

5. Optoacoustic Effect in a Hybrid Multilayered Membrane Deposited on a Hollow-Core Microstructured Optical Waveguide;ACS Photonics;2021-11-03