Infrared Spectroscopy of Aqueous Antibiotic Solutions-Reference-Cited by-同舟云学术

Infrared Spectroscopy of Aqueous Antibiotic Solutions

Published:1984-01 Issue:1 Volume:38 Page:32-35
ISSN:0003-7028
Container-title:Applied Spectroscopy
language:en
Short-container-title:Appl Spectrosc

Author:

Wong James S.¹,Rein Alan J.¹,Wilks Donald¹,Wilks Paul¹

Affiliation:

1. IBM Instruments, Inc., Danbury, Connecticut 06810 (J.S.W., A.J.R.), and General Analysis Corp., Darien, Connecticut 06820 (D.W., P.W.)

Abstract

Infrared spectra of aqueous antibiotic solutions were obtained using a new Liquid Analyzer accessory in a Fourier transform infrared (FT-IR) spectrometer. Based on a cylindrical internal reflectance element, the Liquid Analyzer accessory provides a sufficiently short (∼0.015 mm) effective pathlength for infrared spectroscopy of aqueous solutions from 3200 to 800 cm−1, Spectra of aqueous solutions of penicillin VK, sodium oxacillin and sodium methicillin are shown. By measuring the absorbante of the beta-lactam carbonyl band, FT-IR spectroscopy with the accessory exhibits analytical sensitivity to less than 0.1% concentration by weight of antibiotic both in aqueous solution and in an actual fermentation broth.

Publisher

SAGE Publications

Subject

Spectroscopy,Instrumentation

Link

http://journals.sagepub.com/doi/pdf/10.1366/0003702844554350

Reference2 articles.

Cited by 44 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Infrared Spectroscopy in Aqueous Solutions: Capabilities and Challenges;Critical Reviews in Analytical Chemistry;2022-02-25

2. Vibrational Spectroscopic Monitoring of the Gelation Transition in Nafion Ionomer Dispersions;Applied Spectroscopy;2020-10-12

3. On-line measurement of the substrate concentrations in Pichia pastoris fermentations using FT-IR/ATR;Biotechnology Letters;2012-02-08

4. On-Line Analysis of Broth;Biotechnology;2008-03-20

5. Sequential Injection/Mid-Infrared Spectroscopic Analysis of an Acetone‐Butanol‐Ethanol Fermentation: Analyte Cross‐Correlation Effects;Spectroscopy Letters;2005-11