1. Division of Biochemistry, The Jikei University School of Medicine, Nishi-Shinbashi, Minato-ku, Tokyo, Japan 105 (Y.O., K. Iriyama); Department of Ophthalmology, The Jikei University School of Medicine, Nishi-Shinbashi, Minato-ku, Tokyo, Japan 105 (A.M., S.M.); and Department of Chemistry, School of Science and Engineering, Waseda University, Okubo, Shinjukuku, Tokyo, Japan 160 (K. Itoh)