The genotypical characteristic of M. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosis-Reference-Cited by-同舟云学术

The genotypical characteristic of M. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosis

Published:2011-02-28 Issue:1 Volume:10 Page:12-17
ISSN:1819-3684
Container-title:Bulletin of Siberian Medicine
language:
Short-container-title:Bûll. sib. med.

Author:

Voronkova O. V.,Urazova O. I.,Khasanova R. R.,Novitsky V. V.,Churina Ye. G.,Naslednikova I. O.,Filinyuk O. V.,Serebryakova V. A.,Kolobovnikova Yu. V.

Abstract

The results of 77 M. tuberculosis clinical isolates genetic typing, allocated from patients with extensive destructive infiltrative and disseminated pulmonary tuberculosis are presented in the article. It is established that among genetically non-uniform Mycobacterium tuberculosis strains, circulating in Tomsk and the Tomsk Region, and causing acute progressive destructive pulmonary tuberculosis, 19% show multi drag resistance. Beijing family strains make 27% from the general population, have a high clusterization index (74%), level of their multi drag resistance in 3 times exceeds that at «not Beijing» strains for which the share of clustering strains makes 11%.

Publisher

Siberian State Medical University

Subject

Molecular Medicine

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